| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TOE1 |
| Gene ID: | 114034 |
| Uniprot ID: | TOE1_HUMAN |
| Immunogen Region: | 130-430 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 130-430 of human TOE1 (NP_079353.3). |
| Immunogen Sequence: | EYVIEPKSVQFLIQHGFNFN QQYAQGIPYHKGNDKGDESQ SQSVRTLFLELIRARRPLVL HNGLIDLVFLYQNFYAHLPE SLGTFTADLCEMFPAGIYDT KYAAEFHARFVASYLEYAFR KCERENGKQRAAGSPHLTLE FCNYPSSMRDHIDYRCCLPP ATHRPHPTSICDNFSAYGWC PLGPQCPQSHDIDLIIDTDE AAAEDKRRRRRRREKRKRAL LNLPGTQTSGEAKDGPPKK |
| Tissue Specificity | Widely expressed. |
| Function | Inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1. Involved in the maturation of snRNAs and snRNA 3'-tail processing. |
| Protein Name | Target Of Egr1 Protein 1 |
| Cellular Localisation | NucleusNucleolusNucleus SpeckleLocalizes To Nuclear Speckles |
| Alternative Antibody Names | Anti-Target Of Egr1 Protein 1 antibodyAnti-TOE1 antibody |
Information sourced from Uniprot.org