| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TOE1 (130-430) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TOE1 |
| Gene ID: |
114034 |
| Uniprot ID: |
TOE1_HUMAN |
| Immunogen Region: |
130-430 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 130-430 of human TOE1 (NP_079353.3). |
| Immunogen Sequence: |
EYVIEPKSVQFLIQHGFNFN QQYAQGIPYHKGNDKGDESQ SQSVRTLFLELIRARRPLVL HNGLIDLVFLYQNFYAHLPE SLGTFTADLCEMFPAGIYDT KYAAEFHARFVASYLEYAFR KCERENGKQRAAGSPHLTLE FCNYPSSMRDHIDYRCCLPP ATHRPHPTSICDNFSAYGWC PLGPQCPQSHDIDLIIDTDE AAAEDKRRRRRRREKRKRAL LNLPGTQTSGEAKDGPPKK |
| Tissue Specificity | Widely expressed. |
| Function | Inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1. Involved in the maturation of snRNAs and snRNA 3'-tail processing. |
| Protein Name | Target Of Egr1 Protein 1 |
| Cellular Localisation | NucleusNucleolusNucleus SpeckleLocalizes To Nuclear Speckles |
| Alternative Antibody Names | Anti-Target Of Egr1 Protein 1 antibodyAnti-TOE1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
