Anti-TNFSF12 antibody (41-90 aa) (STJ96150)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human TNFSF12 at the amino acid range 41-90
General Information
| Short Description | Rabbit polyclonal anti-Tumor necrosis factor ligand superfamily member 12 (41-90 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TNFSF12 |
| Gene ID | 8742 |
| Uniprot ID | TNF12_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human TNFSF12 at the amino acid range 41-90 |
| Immunogen Region | 41-90 aa |
| Specificity | TWEAK Polyclonal Antibody detects endogenous levels of TWEAK protein. |
Additional Info
| Post Translational Modifications | The soluble form derives from the membrane form by proteolytic processing. |
| Function | Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion. |
| Protein Name | Tumor Necrosis Factor Ligand Superfamily Member 12Apo3 LigandTnf-Related Weak Inducer Of ApoptosisTweak Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 12 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 12 - Secreted Form |
| Database Links | Reactome: R-HSA-5668541Reactome: R-HSA-5676594 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinTumor Necrosis Factor Ligand Superfamily Member 12Secreted Form: SecretedIsoform Twe-Pril: Cell MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Ligand Superfamily Member 12 antibodyAnti-Apo3 Ligand antibodyAnti-Tnf-Related Weak Inducer Of Apoptosis antibodyAnti-Tweak Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 12 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 12 - Secreted Form antibodyAnti-TNFSF12 antibodyAnti-APO3L antibodyAnti-DR3LG antibodyAnti-UNQ181 antibodyAnti-PRO207 antibody |
Information sourced from Uniprot.org