Immunohistochemistry analysis of 4-1BB/CD137 in paraffin-embedded Human spleen using 4-1BB/CD137 Rabbit polyclonal antibody (STJ117796) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.

Anti-TNFRSF9 antibody (164-255) (STJ117796)

⇓ Datasheet ⇓ SDS
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ117796
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General Information

Short DescriptionRabbit polyclonal 4-1BB/CD137 (164-255) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC-P/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:2000
IHC-P:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolTNFRSF9
Gene ID3604
Uniprot IDTNR9_HUMAN
Immunogen Region164-255
Immunogen SequenceSMCEQDCKQGQELTKKGCKD CCFGTFNDQKRGICRPWTNC SLDGKSVLVNGTKERDVVCG PSPADLSPGASSVTPPAPAR EPGHSPQIISFFLALTSTAL LFLLFFLTLRFSVVKRGRKK LLYIFKQPFMRPVQTTQEED GCSCRFPEEEEGGCEL
SpecificityA synthetic peptide corresponding to a sequence within amino acids 100-200 of human 4-1BB/CD137 (NP_001552.2).

Additional Info

Tissue Specificity Expressed on the surface of activated T-cells.
Function Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable).
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 9
4-1bb Ligand Receptor
Cdw137
T-Cell Antigen 4-1bb Homolog
T-Cell Antigen Ila
Cd Antigen Cd137
Database Links Reactome: R-HSA-5669034
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Tumor Necrosis Factor Receptor Superfamily Member 9 antibody
Anti-4-1bb Ligand Receptor antibody
Anti-Cdw137 antibody
Anti-T-Cell Antigen 4-1bb Homolog antibody
Anti-T-Cell Antigen Ila antibody
Anti-Cd Antigen Cd137 antibody
Anti-TNFRSF9 antibody
Anti-CD137 antibody
Anti-ILA antibody

Information sourced from Uniprot.org

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