• Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:200
  • Western blot analysis of Hela lysate, antibody was diluted at 1000. Secondary antibody was diluted at 1:20000

Anti-TNFRSF11A antibody (60-120 aa) (STJ98715)

SKU:
STJ98715

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Tumor necrosis factor receptor superfamily member 11A (60-120 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:500-200
ELISA 1:10000-20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TNFRSF11A
Gene ID: 8792
Uniprot ID: TNR11_HUMAN
Immunogen Region: 60-120 aa
Specificity: The antibody detects endogenous RANK
Immunogen: Synthetic peptide from the human protein at the amino acid range 60-120
Function Receptor for TNFSF11/RANKL/TRANCE/OPGL.essential for RANKL-mediated osteoclastogenesis. Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2. Involved in the regulation of interactions between T-cells and dendritic cells.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 11a
Osteoclast Differentiation Factor Receptor
Odfr
Receptor Activator Of Nf-Kb
Cd Antigen Cd265
Database Links Reactome: R-HSA-5668541
Reactome: R-HSA-5676594
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Membrane Raft
Isoform Rank-E5a: Cell Membrane
Alternative Antibody Names Anti-Tumor Necrosis Factor Receptor Superfamily Member 11a antibody
Anti-Osteoclast Differentiation Factor Receptor antibody
Anti-Odfr antibody
Anti-Receptor Activator Of Nf-Kb antibody
Anti-Cd Antigen Cd265 antibody
Anti-TNFRSF11A antibody
Anti-RANK antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance