• Western blot analysis of C2C12, using Human TNFRSF11A antibody (STJ11104869) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 60s.

Anti-TNFRSF11A antibody (30-212) (STJ11104869)

SKU:
STJ11104869

£112.50 - £522.50
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Tumor Necrosis Factor Receptor Superfamily Member 11a (30-212) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:100-1:500
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TNFRSF11A
Gene ID: 8792
Uniprot ID: TNR11_HUMAN
Immunogen Region: 30-212
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-212 of human TNFRSF11A. (NP_003830.1).
Immunogen Sequence: IAPPCTSEKHYEHLGRCCNK CEPGKYMSSKCTTTSDSVCL PCGPDEYLDSWNEEDKCLLH KVCDTGKALVAVVAGNSTTP RRCACTAGYHWSQDCECCRR NTECAPGLGAQHPLQLNKDT VCKPCLAGYFSDAFSSTDKC RPWTNCTFLGKRVEHHGTEK SDAVCSSSLPARKPPNEPHV YLP
Tissue Specificity Ubiquitous expression with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland.
Function Receptor for TNFSF11/RANKL/TRANCE/OPGL.essential for RANKL-mediated osteoclastogenesis. Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2. Involved in the regulation of interactions between T-cells and dendritic cells.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 11a
Osteoclast Differentiation Factor Receptor
Odfr
Receptor Activator Of Nf-Kb
Cd Antigen Cd265
Database Links Reactome: R-HSA-5668541
Reactome: R-HSA-5676594
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Membrane Raft
Isoform Rank-E5a: Cell Membrane
Alternative Antibody Names Anti-Tumor Necrosis Factor Receptor Superfamily Member 11a antibody
Anti-Osteoclast Differentiation Factor Receptor antibody
Anti-Odfr antibody
Anti-Receptor Activator Of Nf-Kb antibody
Anti-Cd Antigen Cd265 antibody
Anti-TNFRSF11A antibody
Anti-RANK antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance