| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-TMPRSS3 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 48kDa band observed in A431 lysates (calculated MW of 49.4kDa according to NP_076927.1). Recommended concentration: 0.1-0.3µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | TMPRSS3 |
| Gene ID: | 64699 |
| Uniprot ID: | TMPS3_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_076927.1; NP_115777.1; NP_115780.1; NP_115781.1 |
| Specificity: | This antibody is expected to recognise all four reported isoforms (NP_076927.1; NP_115777.1; NP_115780.1; NP_115781.1) |
| Immunogen Sequence: | EKIVYHSKYKPKR |
| Post Translational Modifications | Undergoes autoproteolytic activation. |
| Function | Probable serine protease that plays a role in hearing. Acts as a permissive factor for cochlear hair cell survival and activation at the onset of hearing and is required for saccular hair cell survival. Activates ENaC (in vitro). |
| Protein Name | Transmembrane Protease Serine 3Serine Protease Tadg-12Tumor-Associated Differentially-Expressed Gene 12 Protein |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Transmembrane Protease Serine 3 antibodyAnti-Serine Protease Tadg-12 antibodyAnti-Tumor-Associated Differentially-Expressed Gene 12 Protein antibodyAnti-TMPRSS3 antibodyAnti-ECHOS1 antibodyAnti-TADG12 antibodyAnti-UNQ323 antibodyAnti-PRO382 antibody |
Information sourced from Uniprot.org