| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TMED9 (1-224) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TMED9 |
| Gene ID: |
54732 |
| Uniprot ID: |
TMED9_HUMAN |
| Immunogen Region: |
1-224 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of human TMED9 (NP_059980.2). |
| Immunogen Sequence: |
MAVELGVLLVRPRPGTGLGR VMRTLLLVLWLATRGSALYF HIGETEKKCFIEEIPDETMV IGNYRTQLYDKQREEYQPAT PGLGMFVEVKDPEDKVILAR QYGSEGRFTFTSHTPGEHQI CLHSNSTKFSLFAGGMLRVH LDIQVGEHANDYAEIAAKDK LSELQLRVRQLVEQVEQIQK EQNYQRWREERFRQTSESTN QRVLWWSILQTLILVAIGVW QMRH |
| Post Translational Modifications | N-linked glycosylated containing high mannose. |
| Function | Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway. In COPI vesicle-mediated retrograde transport involved in the coatomer recruitment to membranes of the early secretory pathway. Increases coatomer-dependent activity of ARFGAP2. Thought to play a crucial role in the specific retention of p24 complexes in cis-Golgi membranes.specifically contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. May be involved in organization of intracellular membranes, such as of the ER-Golgi intermediate compartment and the Golgi apparatus. Involved in ER localization of PTPN2 isoform PTPB. |
| Protein Name | Transmembrane Emp24 Domain-Containing Protein 9Gmp25Glycoprotein 25l2P24 Family Protein Alpha-2P24alpha2P25 |
| Database Links | Reactome: R-HSA-6807878Reactome: R-HSA-6811434 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type I Membrane ProteinGolgi ApparatusCis-Golgi Network MembraneEndoplasmic Reticulum-Golgi Intermediate Compartment MembraneTrans-Golgi Network MembraneCycles Between Compartments Of The Early Secretatory Pathway |
| Alternative Antibody Names | Anti-Transmembrane Emp24 Domain-Containing Protein 9 antibodyAnti-Gmp25 antibodyAnti-Glycoprotein 25l2 antibodyAnti-P24 Family Protein Alpha-2 antibodyAnti-P24alpha2 antibodyAnti-P25 antibodyAnti-TMED9 antibodyAnti-GP25L2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
