Anti-TM9SF4 antibody (315-365 aa) (STJ195304)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human TM9S4 at the amino acid range 315-365
General Information
| Short Description | Rabbit polyclonal anti-Transmembrane 9 superfamily member 4 (315-365 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TM9SF4 |
| Gene ID | 9777 |
| Uniprot ID | TM9S4_HUMAN |
| Immunogen | Synthesized peptide derived from the human TM9S4 at the amino acid range 315-365 |
| Immunogen Region | 315-365 aa |
| Specificity | This antibody detects endogenous levels of TM9S4 at Human/Mouse/Rat |
Additional Info
| Function | Associates with proteins harboring glycine-rich transmembrane domains and ensures their efficient localization to the cell surface. Regulates the assembly and activity of V-ATPase in colon cancer cells via its interaction with V-type proton ATPase subunit H (ATP6V1H) and contributes to V-ATPase-mediated pH alterations in cancer cells which play an important role in drug resistance and invasiveness of colon cancer cells. Plays an important role in an atypical phagocytic activity of metastatic melanoma cells called cannibalism and is involved in the pH regulation of the intracellular vesicles in tumor cells. |
| Protein Name | Transmembrane 9 Superfamily Member 4Tumor Cannibalism Associated Protein 1 |
| Database Links | |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinGolgi ApparatusEarly Endosome |
| Alternative Antibody Names | Anti-Transmembrane 9 Superfamily Member 4 antibodyAnti-Tumor Cannibalism Associated Protein 1 antibodyAnti-TM9SF4 antibodyAnti-KIAA0255 antibodyAnti-TUCAP1 antibody |
Information sourced from Uniprot.org