| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Transmembrane 9 superfamily member 4 (315-365 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TM9SF4 |
| Gene ID: |
9777 |
| Uniprot ID: |
TM9S4_HUMAN |
| Immunogen Region: |
315-365 aa |
| Specificity: |
This antibody detects endogenous levels of TM9S4 at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human TM9S4 at the amino acid range 315-365 |
| Function | Associates with proteins harboring glycine-rich transmembrane domains and ensures their efficient localization to the cell surface. Regulates the assembly and activity of V-ATPase in colon cancer cells via its interaction with V-type proton ATPase subunit H (ATP6V1H) and contributes to V-ATPase-mediated pH alterations in cancer cells which play an important role in drug resistance and invasiveness of colon cancer cells. Plays an important role in an atypical phagocytic activity of metastatic melanoma cells called cannibalism and is involved in the pH regulation of the intracellular vesicles in tumor cells. |
| Protein Name | Transmembrane 9 Superfamily Member 4Tumor Cannibalism Associated Protein 1 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinGolgi ApparatusEarly Endosome |
| Alternative Antibody Names | Anti-Transmembrane 9 Superfamily Member 4 antibodyAnti-Tumor Cannibalism Associated Protein 1 antibodyAnti-TM9SF4 antibodyAnti-KIAA0255 antibodyAnti-TUCAP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
