Anti-TM4SF19 antibody (140-160 aa) (STJ194762)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human TM4SF19 at the amino acid range 140-160
General Information
| Short Description | Rabbit polyclonal anti-Transmembrane 4 L6 family member 19 (140-160 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA-Pep 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TM4SF19 |
| Gene ID | 116211 |
| Uniprot ID | T4S19_HUMAN |
| Immunogen | Synthesized peptide derived from the human TM4SF19 at the amino acid range 140-160 |
| Immunogen Region | 140-160 aa |
| Specificity | This antibody detects endogenous levels of human TM4SF19 |
Additional Info
| Function | Negatively regulates vacuolar (H+)-ATPase (V-ATPase) activity by interacting with members of V-ATPase V0 complex and hence inhibiting V1-V0 complex assembly. Required for multinucleation during osteoclast differentiation. |
| Protein Name | Transmembrane 4 L6 Family Member 19Osteoclast Maturation-Associated Gene 4 ProteinTetraspan Membrane Protein Octm4 |
| Database Links | |
| Cellular Localisation | Lysosome MembraneMulti-Pass Membrane ProteinCytoplasmCytoskeletonCell ProjectionFilopodiumIn OsteoclastsLocalizes Not Only To The Actin RingBut Also To The FilopodiaThe Stretched Structures For Searching Cells To FuseAnd The FusopodThe Cytoplasmic Bridge For Contacting Other Osteoclasts To Fuse |
| Alternative Antibody Names | Anti-Transmembrane 4 L6 Family Member 19 antibodyAnti-Osteoclast Maturation-Associated Gene 4 Protein antibodyAnti-Tetraspan Membrane Protein Octm4 antibodyAnti-TM4SF19 antibodyAnti-OCTM4 antibody |
Information sourced from Uniprot.org