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Anti-TLN1 antibody (1-220) (STJ25860)

Immunofluorescence analysis of human colon carcinoma using TLN1 antibody (STJ25860) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of rat Intestine using TLN1 antibody (STJ25860) at dilution of 1:100. Blue: DAPI for nuclear staining.
Western blot analysis of extracts of U-87MG cells, using TLN1 antibody (STJ25860) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 20s.

Anti-TLN1 antibody (1-220) (STJ25860)

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STJ25860

£112.50 - £522.50

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General Information
Product Properties
Target Information
Additional Info
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Host:	Rabbit
Applications:	WB/IF
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-TLN1 (1-220) is suitable for use in Western Blot and Immunofluorescence research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IF/ICC 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	TLN1
Gene ID:	7094
Uniprot ID:	TLN1_HUMAN
Immunogen Region:	1-220
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human TLN1 (NP_006280.3).
Immunogen Sequence:	MVALSLKISIGNVVKTMQFE PSTMVYDACRIIRERIPEAP AGPPSDFGLFLSDDDPKKGI WLEAGKALDYYMLRNGDTME YRKKQRPLKIRMLDGTVKTI MVDDSKTVTDMLMTICARIG ITNHDEYSLVRELMEEKKEE ITGTLRKDKTLLRDEKKMEK LKQKLHTDDELNWLDHGRTL REQGVEEHETLLLRRKFFYS DQNVDSRDPVQLNLLYVQAR

Tissue Specificity	Isoform 2: Expressed at low to non-detectable levels in many tissues but highly expressed in skin and pancreas with other tissues including kidney cortex, endocervix, testis, pituitary, liver, and spleen also showing robust expression.
Function	High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts. Involved in connections of major cytoskeletal structures to the plasma membrane.
Protein Name	Talin-1
Database Links	Reactome: R-HSA-114608 Reactome: R-HSA-354192 Reactome: R-HSA-354194 Reactome: R-HSA-372708 Reactome: R-HSA-381038 Reactome: R-HSA-399955 Reactome: R-HSA-445355 Reactome: R-HSA-5674135 Reactome: R-HSA-6802946 Reactome: R-HSA-6802948 Reactome: R-HSA-6802952 Reactome: R-HSA-6802955 Reactome: R-HSA-9649948 Reactome: R-HSA-9656223
Cellular Localisation	Cell Projection Ruffle Membrane Peripheral Membrane Protein Cytoplasmic Side Cytoplasm Cytoskeleton Cell Surface Cell Junction Focal Adhesion Colocalizes With Layn At The Membrane Ruffles Localized Preferentially In Focal Adhesions Than Fibrillar Adhesions
Alternative Antibody Names	Anti-Talin-1 antibody Anti-TLN1 antibody Anti-KIAA1027 antibody Anti-TLN antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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