| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TIMM44 |
| Gene ID: | 10469 |
| Uniprot ID: | TIM44_HUMAN |
| Immunogen Region: | 153-452 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 153-452 of human TIMM44 (NP_006342.2). |
| Immunogen Sequence: | AKTAKQSAESVSKGGEKLGR TAAFRALSQGVESVKKEIDD SVLGQTGPYRRPQRLRKRTE FAGDKFKEEKVFEPNEEALG VVLHKDSKWYQQWKDFKENN VVFNRFFEMKMKYDESDNAF IRASRALTDKVTDLLGGLFS KTEMSEVLTEILRVDPAFDK DRFLKQCENDIIPNVLEAMI SGELDILKDWCYEATYSQLA HPIQQAKALGLQFHSRILDI DNVDLAMGKMMEQGPVLII |
| Function | Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source. |
| Protein Name | Mitochondrial Import Inner Membrane Translocase Subunit Tim44 |
| Database Links | Reactome: R-HSA-1268020 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinMatrix SideMitochondrion Matrix |
| Alternative Antibody Names | Anti-Mitochondrial Import Inner Membrane Translocase Subunit Tim44 antibodyAnti-TIMM44 antibodyAnti-MIMT44 antibodyAnti-TIM44 antibody |
Information sourced from Uniprot.org