Anti-TIMM17A antibody (1-171) (STJ28532)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TIMM17A (1-171) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TIMM17A |
| Gene ID | 10440 |
| Uniprot ID | TI17A_HUMAN |
| Immunogen Region | 1-171 |
| Immunogen Sequence | MEEYAREPCPWRIVDDCGGA FTMGTIGGGIFQAIKGFRNS PVGVNHRLRGSLTAIKTRAP QLGGSFAVWGGLFSMIDCSM VQVRGKEDPWNSITSGALTG AILAARNGPVAMVGSAAMGG ILLALIEGAGILLTRFASAQ FPNGPQFAEDPSQLPSTQLP SSPFGDYRQYQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-171 of human TIMM17A (NP_006326.1). |
Additional Info
| Post Translational Modifications | Degraded by YMEL1 downstream of the integrated stress response (ISR). |
| Function | Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. |
| Protein Name | Mitochondrial Import Inner Membrane Translocase Subunit Tim17-AInner Membrane Preprotein Translocase Tim17a |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Import Inner Membrane Translocase Subunit Tim17-A antibodyAnti-Inner Membrane Preprotein Translocase Tim17a antibodyAnti-TIMM17A antibodyAnti-MIMT17 antibodyAnti-TIM17 antibodyAnti-TIM17A antibodyAnti-TIMM17 antibody |
Information sourced from Uniprot.org