| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TEKT1 |
| Gene ID: | 83659 |
| Uniprot ID: | TEKT1_HUMAN |
| Immunogen Region: | 1-300 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TEKT1 (NP_444515.1). |
| Immunogen Sequence: | MAKLLQPPPKFLPSEWHIAN KNQYHRADAQRSRSERLVAE SQRLVDEIEKTTRKSQSDVN KKLEQRLEEVQFWKKELDDK LEQLVNVTDDLLIYKIRLEK ALETLKEPLHITETCLAYRE KRIGIDLVHDTVEHELIKEA EIIQGIMALLTRTLEEASEQ IRMNRSAKYNLEKDLKDKFV ALTIDDICFSLNNNSPNIRY SENAVRIEPNSVSLEDWLDF SSTNVEKADKQRNNSLMLK |
| Tissue Specificity | Predominantly expressed in testis. Expressed in airway epithelial cells. |
| Post Translational Modifications | Ubiquitinated, leading to its degradation. Deubiquitinated by USP16, promoting its stability. |
| Function | Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. |
| Protein Name | Tektin-1 |
| Cellular Localisation | CytoplasmCytoskeletonCilium AxonemeFlagellum Axoneme |
| Alternative Antibody Names | Anti-Tektin-1 antibodyAnti-TEKT1 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and HSP90AB1 knockout (KO) HeLa cells, using [KO Validated] Hsp90 Beta Rabbit polyclonal antibody (STJ119988) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/98773/382821/STJ119988_1__00628.1713151320.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and HSP90AB1 knockout (KO) HeLa cells, using [KO Validated] Hsp90 Beta Rabbit polyclonal antibody (STJ119988) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.")
