• Western blot analysis of the lysates from HUVECcells using TEAD3 antibody.

Anti-TEAD3 antibody (211-260 aa) (STJ95963)

SKU:
STJ95963

Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Transcriptional enhancer factor TEF-5 (211-260 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TEAD3
Gene ID: 7005
Uniprot ID: TEAD3_HUMAN
Immunogen Region: 211-260 aa
Specificity: TEF-5 Polyclonal Antibody detects endogenous levels of TEF-5 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human TEAD3 at the amino acid range 211-260
Function Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer.
Protein Name Transcriptional Enhancer Factor Tef-5
Dtef-1
Tea Domain Family Member 3
Tead-3
Database Links Reactome: R-HSA-2032785
Reactome: R-HSA-8951671
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Transcriptional Enhancer Factor Tef-5 antibody
Anti-Dtef-1 antibody
Anti-Tea Domain Family Member 3 antibody
Anti-Tead-3 antibody
Anti-TEAD3 antibody
Anti-TEAD5 antibody
Anti-TEF5 antibody

Information sourced from Uniprot.org

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