| Host: |
Armenian Hamster |
| Applications: |
FC/IP/IHC |
| Reactivity: |
Mouse |
| Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: |
Armenian Hamster monoclonal antibody anti-TCR Gamma/Delta is suitable for use in Flow Cytometry, Immunoprecipitation and Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
UC7-13D5 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.2 µm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as determined by LAL gel clotting assay. |
| Concentration: |
0.5 mg/mL |
| Storage Instruction: |
Store at 2-8°C. Do not freeze this product. |
| Background | T cell receptor (TCR) is a heterodimer consisting of an Alpha and a Beta chain (TCR Alpha/Beta ) or a Gamma and a Delta chain (TCR Gamma/Delta ). TCR Gamma/Delta belongs to the immunoglobulin superfamily, involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The TCR Gamma/Delta associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most Gamma/Delta T cells are CD4-/CD8-, some are CD8+. T cells expressing the TCR Gamma/Delta have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that Gamma/Delta T cells also play a principal role in antigen presentation. Immobilized UC7-13D5 antibody has been reported to activate TCR-Gamma/Delta-bearing T cells in vitro, and to deplete peripheral TCR-Gamma/Delta-bearing T cells in vivo. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
