Anti-TCOF1 antibody (41-90 aa) (STJ96096)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human TCOF1 at the amino acid range 41-90
General Information
| Short Description | Rabbit polyclonal anti-Treacle protein (41-90 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TCOF1 |
| Gene ID | 6949 |
| Uniprot ID | TCOF_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human TCOF1 at the amino acid range 41-90 |
| Immunogen Region | 41-90 aa |
| Specificity | Treacle Polyclonal Antibody detects endogenous levels of Treacle protein. |
Additional Info
| Function | Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification. Required for neural crest specification: following monoubiquitination by the BCR(KBTBD8) complex, associates with NOLC1 and acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification. |
| Protein Name | Treacle ProteinTreacher Collins Syndrome Protein |
| Database Links | |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Treacle Protein antibodyAnti-Treacher Collins Syndrome Protein antibodyAnti-TCOF1 antibody |
Information sourced from Uniprot.org