| Host: | Mouse |
| Applications: | IHC/IF |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-T-cell leukemia/lymphoma protein 1A (50-114 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
| Clonality : | Monoclonal |
| Clone ID : | ABT234 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2ak |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: | IHC-P 1:100-500IF 1:100-500 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TCL1A |
| Gene ID: | 8115 |
| Uniprot ID: | TCL1A_HUMAN |
| Immunogen Region: | 50-114 aa |
| Specificity: | The antibody can specifically recognize human TCL1 protein. |
| Immunogen: | Synthesized peptide derived from the human TCL1 at the amino acid range 50-114 |
| Function | Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival. |
| Protein Name | T-Cell Leukemia/Lymphoma Protein 1aOncogene Tcl-1Oncogene Tcl1Protein P14 Tcl1 |
| Cellular Localisation | CytoplasmNucleusMicrosomeEndoplasmic ReticulumMicrosomal Fraction |
| Alternative Antibody Names | Anti-T-Cell Leukemia/Lymphoma Protein 1a antibodyAnti-Oncogene Tcl-1 antibodyAnti-Oncogene Tcl1 antibodyAnti-Protein P14 Tcl1 antibodyAnti-TCL1A antibodyAnti-TCL1 antibody |
Information sourced from Uniprot.org