| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TCL1A (1-114) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TCL1A |
| Gene ID: |
8115 |
| Uniprot ID: |
TCL1A_HUMAN |
| Immunogen Region: |
1-114 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-114 of human TCL1A (NP_001092195.1). |
| Immunogen Sequence: |
MAECPTLGEAVTDHPDRLWA WEKFVYLDEKQHAWLPLTIE IKDRLQLRVLLRREDVVLGR PMTPTQIGPSLLPIMWQLYP DGRYRSSDSSFWRLVYHIKI DGVEDMLLELLPDD |
| Tissue Specificity | Restricted in the T-cell lineage to immature thymocytes and activated peripheral lymphocytes. Preferentially expressed early in T- and B-lymphocyte differentiation. |
| Function | Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival. |
| Protein Name | T-Cell Leukemia/Lymphoma Protein 1aOncogene Tcl-1Oncogene Tcl1Protein P14 Tcl1 |
| Cellular Localisation | CytoplasmNucleusMicrosomeEndoplasmic ReticulumMicrosomal Fraction |
| Alternative Antibody Names | Anti-T-Cell Leukemia/Lymphoma Protein 1a antibodyAnti-Oncogene Tcl-1 antibodyAnti-Oncogene Tcl1 antibodyAnti-Protein P14 Tcl1 antibodyAnti-TCL1A antibodyAnti-TCL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
