| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TCF12 |
| Gene ID: | 6938 |
| Uniprot ID: | HTF4_HUMAN |
| Immunogen Region: | 443-682 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 443-682 of human TCF12 (NP_003196.1). |
| Immunogen Sequence: | PIGSLNSNYGGSSLVASSRS ASMVGTHREDSVSLNGNHSV LSSTVTTSSTDLNHKTQENY RGGLQSQSGTVVTTEIKTEN KEKDENLHEPPSSDDMKSDD ESSQKDIKVSSRGRTSSTNE DEDLNPEQKIEREKERRMAN NARERLRVRDINEAFKELGR MCQLHLKSEKPQTKLLILHQ AVAVILSLEQQVRERNLNPK AACLKRREEEKVSAVSAEPP TTLPGTHPGLSETTNPMGH |
| Tissue Specificity | Expressed in several tissues and cell types including skeletal muscle, thymus, and a B-cell line. |
| Function | Transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). May be involved in the functional network that regulates the development of the GnRH axis. |
| Protein Name | Transcription Factor 12Tcf-12Class B Basic Helix-Loop-Helix Protein 20Bhlhb20Dna-Binding Protein Htf4E-Box-Binding ProteinTranscription Factor Htf-4 |
| Database Links | Reactome: R-HSA-525793Reactome: R-HSA-8939236Reactome: R-HSA-9031628Reactome: R-HSA-9839394 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor 12 antibodyAnti-Tcf-12 antibodyAnti-Class B Basic Helix-Loop-Helix Protein 20 antibodyAnti-Bhlhb20 antibodyAnti-Dna-Binding Protein Htf4 antibodyAnti-E-Box-Binding Protein antibodyAnti-Transcription Factor Htf-4 antibodyAnti-TCF12 antibodyAnti-BHLHB20 antibodyAnti-HEB antibodyAnti-HTF4 antibody |
Information sourced from Uniprot.org
