| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S4MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RHOQ |
| Gene ID: | 23433 |
| Uniprot ID: | RHOQ_HUMAN |
| Immunogen Region: | 100-205 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-205 of human TC10/RHOQ (P17081). |
| Immunogen Sequence: | KEEWVPELKEYAPNVPFLLI GTQIDLRDDPKTLARLNDMK EKPICVEQGQKLAKEIGACC YVECSALTQKGLKTVFDEAI IAILTPKKHTVKKRIGSRCI NCCLIT |
| Post Translational Modifications | May be post-translationally modified by both palmitoylation and polyisoprenylation. |
| Function | Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia. |
| Protein Name | Rho-Related Gtp-Binding Protein RhoqRas-Like Protein Tc10Ras-Like Protein Family Member 7a |
| Database Links | Reactome: R-HSA-1445148Reactome: R-HSA-5627083Reactome: R-HSA-9013406 |
| Cellular Localisation | CytoplasmCell MembraneLipid-Anchor |
| Alternative Antibody Names | Anti-Rho-Related Gtp-Binding Protein Rhoq antibodyAnti-Ras-Like Protein Tc10 antibodyAnti-Ras-Like Protein Family Member 7a antibodyAnti-RHOQ antibodyAnti-ARHQ antibodyAnti-RASL7A antibodyAnti-TC10 antibody |
Information sourced from Uniprot.org