| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-TC10/RHOQ (100-205) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S4MR |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RHOQ |
| Gene ID: |
23433 |
| Uniprot ID: |
RHOQ_HUMAN |
| Immunogen Region: |
100-205 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 100-205 of human TC10/RHOQ (P17081). |
| Immunogen Sequence: |
KEEWVPELKEYAPNVPFLLI GTQIDLRDDPKTLARLNDMK EKPICVEQGQKLAKEIGACC YVECSALTQKGLKTVFDEAI IAILTPKKHTVKKRIGSRCI NCCLIT |
| Post Translational Modifications | May be post-translationally modified by both palmitoylation and polyisoprenylation. |
| Function | Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia. |
| Protein Name | Rho-Related Gtp-Binding Protein RhoqRas-Like Protein Tc10Ras-Like Protein Family Member 7a |
| Database Links | Reactome: R-HSA-1445148Reactome: R-HSA-5627083Reactome: R-HSA-9013406 |
| Cellular Localisation | CytoplasmCell MembraneLipid-Anchor |
| Alternative Antibody Names | Anti-Rho-Related Gtp-Binding Protein Rhoq antibodyAnti-Ras-Like Protein Tc10 antibodyAnti-Ras-Like Protein Family Member 7a antibodyAnti-RHOQ antibodyAnti-ARHQ antibodyAnti-RASL7A antibodyAnti-TC10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Immunohistochemistry analysis of ATG7 in paraffin-embedded human esophageal cancer using [KD Validated] ATG7 Rabbit monoclonal antibody (STJ11101724) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/90639/360557/STJ11101724_1__51186.1713125229.jpg?c=1 "Immunohistochemistry analysis of ATG7 in paraffin-embedded human esophageal cancer using [KD Validated] ATG7 Rabbit monoclonal antibody (STJ11101724) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.")
