Anti-TBXAS1 antibody (C-Term) (STJ96154)

SKU:
STJ96154
£48.00 - £252.00
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Thromboxane-A synthase (C-Term) is suitable for use in Western Blot and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TBXAS1
Gene ID: 6916
Uniprot ID: THAS_HUMAN
Immunogen Region: C-Term
Specificity: TXA synthase Polyclonal Antibody detects endogenous levels of TXA synthase protein.
Immunogen: Synthesized peptide derived from the C-terminal region of human TXA synthase.
Function Catalyzes the conversion of prostaglandin H2 (PGH2) to thromboxane A2 (TXA2), a potent inducer of blood vessel constriction and platelet aggregation. Cleaves also PGH2 to 12-hydroxy-heptadecatrienoicacid (12-HHT) and malondialdehyde, which is known to act as a mediator of DNA damage. 12-HHT and malondialdehyde are formed stoichiometrically in the same amounts as TXA2. Additionally, displays dehydratase activity, toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE) producing 15-KETE and 15-HETE.
Protein Name Thromboxane-A Synthase
Txa Synthase
Txs
Cytochrome P450 5a1
Hydroperoxy Icosatetraenoate Dehydratase
Database Links Reactome: R-HSA-211979
Reactome: R-HSA-2162123
Reactome: R-HSA-5579032
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Thromboxane-A Synthase antibody
Anti-Txa Synthase antibody
Anti-Txs antibody
Anti-Cytochrome P450 5a1 antibody
Anti-Hydroperoxy Icosatetraenoate Dehydratase antibody
Anti-TBXAS1 antibody
Anti-CYP5 antibody
Anti-CYP5A1 antibody
Anti-TXAS antibody

Information sourced from Uniprot.org

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