| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TBRG4 |
| Gene ID: | 9238 |
| Uniprot ID: | FAKD4_HUMAN |
| Immunogen Region: | 382-631 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 382-631 of human TBRG4 (NP_004740.2). |
| Immunogen Sequence: | HPDQEDQFFSLVHEKLGSEL PGLEPALQVDLVWALCVLQQ AREAELQAVLHPEFHIQFLG GKSQKDQNTFQKLLHINATA LLEYPEYSGPLLPASAVAPG PSALDRKVTPLQKELQETLK GLLGSADKGSLEVATQYGWV LDAEVLLDSDGEFLPVRDFV APHLAQPTGSQSPPPGSKRL AFLRWEFPNFNSRSKDLLGR FVLARRHIVAAGFLIVDVPF YEWLELKSEWQKGAYLKDK |
| Tissue Specificity | Ubiquitously expressed. Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in smooth muscle. |
| Function | Plays a role in processing of mitochondrial RNA precursors and in stabilization of a subset of mature mitochondrial RNA species, such as MT-CO1, MT-CO2, MT-CYB, MT-CO3, MT-ND3, MT-ND5 and MT-ATP8/6. May play a role in cell cycle progression. |
| Protein Name | Fast Kinase Domain-Containing Protein 4Cell Cycle Progression Restoration Protein 2Cell Cycle Progression Protein 2Protein Tbrg4Transforming Growth Factor Beta Regulator 4 |
| Database Links | Reactome: R-HSA-9837092 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Fast Kinase Domain-Containing Protein 4 antibodyAnti-Cell Cycle Progression Restoration Protein 2 antibodyAnti-Cell Cycle Progression Protein 2 antibodyAnti-Protein Tbrg4 antibodyAnti-Transforming Growth Factor Beta Regulator 4 antibodyAnti-TBRG4 antibodyAnti-CPR2 antibodyAnti-FASTKD4 antibodyAnti-KIAA0948 antibody |
Information sourced from Uniprot.org