| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-TAS2R45 (2-50 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | TAS2R45 |
| Uniprot ID: | T2R45_HUMAN |
| Immunogen Region: | 2-50 aa |
| Specificity: | Specific for TAS2R45 (See also the Immunogen) |
| Immunogen: | A synthetic peptide from aa region 2-50 of human TAS2R45 conjugated to blue carrier protein was used as the antigen. The peptide is homologous with T2R43 and shares about 88% identity with T2R30 and 31. |
| Function | Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. |
| Protein Name | Taste Receptor Type 2 Member 45T2r45G-Protein Coupled Receptor 59 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Taste Receptor Type 2 Member 45 antibodyAnti-T2r45 antibodyAnti-G-Protein Coupled Receptor 59 antibodyAnti-TAS2R45 antibodyAnti-GPR59 antibody |
Information sourced from Uniprot.org