Anti-TAS2R43 antibody (124-173 aa) (STJ95875)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human TAS2R43 at the amino acid range 124-173
General Information
| Short Description | Rabbit polyclonal anti-Taste receptor type 2 member 43 (124-173 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TAS2R43 |
| Gene ID | 259289 |
| Uniprot ID | T2R43_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human TAS2R43 at the amino acid range 124-173 |
| Immunogen Region | 124-173 aa |
| Specificity | T2R43 Polyclonal Antibody detects endogenous levels of T2R43 protein. |
Additional Info
| Function | Gustducin-coupled receptor immplicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Activated by the sulfonyl amide sweeteners saccharin and acesulfame K. In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency. May act as chemosensory receptors in airway epithelial cells to detect and eliminate potential noxious agents from the airways. |
| Protein Name | Taste Receptor Type 2 Member 43T2r43Taste Receptor Type 2 Member 52T2r52 |
| Database Links | Reactome: R-HSA-418594Reactome: R-HSA-420499Reactome: R-HSA-9717207 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinCell ProjectionCilium MembraneIn Airway Epithelial CellsLocalizes To Motile Cilia |
| Alternative Antibody Names | Anti-Taste Receptor Type 2 Member 43 antibodyAnti-T2r43 antibodyAnti-Taste Receptor Type 2 Member 52 antibodyAnti-T2r52 antibodyAnti-TAS2R43 antibody |
Information sourced from Uniprot.org