| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:100IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TARS1 |
| Gene ID: | 6897 |
| Uniprot ID: | SYTC_HUMAN |
| Immunogen Region: | 1-230 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human TARS (NP_689508.3). |
| Immunogen Sequence: | MFEEKASSPSGKMGGEEKPI GAGEEKQKEGGKKKNKEGSG DGGRAELNPWPEYIYTRLEM YNILKAEHDSILAEKAEKDS KPIKVTLPDGKQVDAESWKT TPYQIACGISQGLADNTVIA KVNNVVWDLDRPLEEDCTLE LLKFEDEEAQAVYWHSSAHI MGEAMERVYGGCLCYGPPIE NGFYYDMYLEEGGVSSNDFS SLEALCKKIIKEKQAFERLE VKKETLLAMF |
| Post Translational Modifications | ISGylated. |
| Function | Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain, at the post-transfer stage. |
| Protein Name | Threonine--Trna Ligase 1 - CytoplasmicThreonyl-Trna SynthetaseThrrsThreonyl-Trna Synthetase 1 |
| Database Links | Reactome: R-HSA-379716 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Threonine--Trna Ligase 1 - Cytoplasmic antibodyAnti-Threonyl-Trna Synthetase antibodyAnti-Thrrs antibodyAnti-Threonyl-Trna Synthetase 1 antibodyAnti-TARS1 antibodyAnti-TARS antibody |
Information sourced from Uniprot.org