Host: |
Rabbit |
Applications: |
WB/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Neuromedin-K receptor (401-450) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IF 1:200-1:1000ELISA 1:10000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
TACR3 |
Gene ID: |
6870 |
Uniprot ID: |
NK3R_HUMAN |
Immunogen Region: |
401-450 |
Specificity: |
NK-3R Polyclonal Antibody detects endogenous levels of NK-3R protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from human NK3R. AA range:401-450 |
Post Translational Modifications | The anchoring of this receptor to the plasma membrane is probably mediated by the palmitoylation of a cysteine residue. |
Function | This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P. |
Protein Name | Neuromedin-K ReceptorNkrNk-3 ReceptorNk-3rNeurokinin B ReceptorTachykinin Receptor 3 |
Database Links | Reactome: R-HSA-380095Reactome: R-HSA-416476 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Neuromedin-K Receptor antibodyAnti-Nkr antibodyAnti-Nk-3 Receptor antibodyAnti-Nk-3r antibodyAnti-Neurokinin B Receptor antibodyAnti-Tachykinin Receptor 3 antibodyAnti-TACR3 antibodyAnti-NK3R antibodyAnti-TAC3R antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance