| Post Translational Modifications | Substance P: The substance P form is cleaved at Pro-59 by the prolyl endopeptidase FAP (seprase) activity (in vitro). Substance P is also cleaved and degraded by Angiotensin-converting enzyme (ACE) and neprilysin (MME). |
| Function | Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. |
| Protein Name | Protachykinin-1Ppt Cleaved Into - Substance P - Neurokinin ANkaNeuromedin LSubstance K - Neuropeptide KNpk - Neuropeptide Gamma - C-Terminal-Flanking Peptide |
| Database Links | Reactome: R-HSA-380095Reactome: R-HSA-416476 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Protachykinin-1 antibodyAnti-Ppt Cleaved Into - Substance P - Neurokinin A antibodyAnti-Nka antibodyAnti-Neuromedin L antibodyAnti-Substance K - Neuropeptide K antibodyAnti-Npk - Neuropeptide Gamma - C-Terminal-Flanking Peptide antibodyAnti-TAC1 antibodyAnti-NKA antibodyAnti-NKNA antibodyAnti-TAC2 antibody |
Information sourced from Uniprot.org
