| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TBXT |
| Gene ID: | 6862 |
| Uniprot ID: | TBXT_HUMAN |
| Immunogen Region: | 226-435 |
| Specificity: | RecombinanBrachyury fusion proBrachyuryein conBrachyuryaining a sequence corresponding Brachyuryo amino acids 226-435 of human Brachyury (NP_003172.1). |
| Immunogen Sequence: | HKEMMEEPGDSQQPGYSQWG WLLPGTSTLCPPANPHPQFG GALSLPSTHSCDRYPTLRSH RSSPYPSPYAHRNNSPTYSD NSPACLSMLQSHDNWSSLGM PAHPSMLPVSHNASPPTSSS QYPSLWSVSNGAVTPGSQAA AVSNGLGAQFFRGSPAHYTP LTHPVSAPSSSGSPLYEGAA AATDIVDSQYDAAAQGRLIA SWTPVSPPSM |
| Tissue Specificity | Detected in testis, but not in other, normal tissues. Detected in lung tumors (at protein level). |
| Function | Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence and activates gene transcription when bound to such a site. |
| Protein Name | T-Box Transcription Factor TBrachyury ProteinProtein T |
| Database Links | Reactome: R-HSA-9733709Reactome: R-HSA-9754189Reactome: R-HSA-9758919Reactome: R-HSA-9793380Reactome: R-HSA-9796292Reactome: R-HSA-9823730 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-T-Box Transcription Factor T antibodyAnti-Brachyury Protein antibodyAnti-Protein T antibodyAnti-TBXT antibodyAnti-T antibody |
Information sourced from Uniprot.org
