| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SYNPO |
| Gene ID: | 11346 |
| Uniprot ID: | SYNPO_HUMAN |
| Immunogen Region: | 1-260 |
| Immunogen Sequence: | MLGPHLPPPPLAPSEGRPTP CAFQIPDGSYRCLALEAEES SGEEGLQGEVGPTDLEEDEG VSRSGDDSACRVTQGTPQLP KALGIQPPSCSREEQGASQH DDRASQDWDVVKAGQMMTAS PSPGPGPRVAQKPALGRSTS LTEKDLKEAKARSQQIAAQL TTPPSSNSRGVQLFNRRRQR VNEFTLESHGQRGQKPSQES LRVLPSSLPGHAPGLSLSST SLPEPGPPRHPSPQSPDRG |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human SYNPO (NP_001159680.1). |
| Tissue Specificity | Expressed in cerebral cortex. |
| Post Translational Modifications | O-glycosylated. |
| Function | Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity. |
| Protein Name | Synaptopodin |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonCell JunctionTight JunctionPerikaryonCell ProjectionDendritic SpinePostsynaptic DensitySynapseCytosolLocalized At The Tight Junction Of CellsIn BrainLocalized To The Postsynaptic Densities And In The PerikaryaAssociated With Dendritic Spines Of A Subset Of Synapses |
| Alternative Antibody Names | Anti-Synaptopodin antibodyAnti-SYNPO antibodyAnti-KIAA1029 antibody |
Information sourced from Uniprot.org
