| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse/Rat/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-Swiprosin 1/EFHD2 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 30kDa band observed in Human Thymus, Human Lymph node and Human Tonsil lysates (calculated MW of 26.7kDa according to NP_077305.2). Recommended concentration: 0.5-1.5µg/ml. Pri |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | EFHD2 |
| Gene ID: | 79180 |
| Uniprot ID: | EFHD2_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_077305.2 |
| Specificity: | This antibody does not cross-react with Mouse Swiprosin 2. Data kindly provided by Sebastian Duetting and Dirk Mielenz. |
| Immunogen Sequence: | CAAFKELQSTFK |
| Function | May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance. |
| Protein Name | Ef-Hand Domain-Containing Protein D2Swiprosin-1 |
| Database Links | Reactome: R-HSA-9013405 |
| Cellular Localisation | Membrane RaftIn A Mouse Immature B-Cell Line Wehi-231 |
| Alternative Antibody Names | Anti-Ef-Hand Domain-Containing Protein D2 antibodyAnti-Swiprosin-1 antibodyAnti-EFHD2 antibodyAnti-SWS1 antibody |
Information sourced from Uniprot.org