Anti-SV2B antibody (1-50 aa) (STJ191487)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein.at the amino acid range 1-50
General Information
| Short Description | Rabbit polyclonal anti-Synaptic vesicle glycoprotein 2B (1-50 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SV2B |
| Gene ID | 9899 |
| Uniprot ID | SV2B_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein.at the amino acid range 1-50 |
| Immunogen Region | 1-50 aa |
| Specificity | SV2B Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Probably plays a role in the control of regulated secretion in neural and endocrine cells. (Microbial infection) Receptor for the C.botulinum neurotoxin type A2 (BoNT/A, botA).glycosylation is not essential but enhances the interaction. Probably also serves as a receptor for the closely related C.botulinum neurotoxin type A1. |
| Protein Name | Synaptic Vesicle Glycoprotein 2b |
| Database Links | Reactome: R-HSA-5250955Reactome: R-HSA-5250968Reactome: R-HSA-5250981Reactome: R-HSA-5250992 |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneMulti-Pass Membrane ProteinAcrosomeAssociated With Synaptic-Like Microvesicles But Not With Insulin-Containing Vesicles In Insulin-Secreting Cells Of The PancreasLocalizes To Microvesicles In The PinealocytesLocalizes To The Acrosome In Spermatids |
| Alternative Antibody Names | Anti-Synaptic Vesicle Glycoprotein 2b antibodyAnti-SV2B antibodyAnti-KIAA0735 antibody |
Information sourced from Uniprot.org