| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | STXBP3 |
| Gene ID: | 6814 |
| Uniprot ID: | STXB3_HUMAN |
| Immunogen Region: | 343-592 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 343-592 of human STXBP3 (NP_009200.2). |
| Immunogen Sequence: | KQVVHLNLAEDCMNKFKLNI EKLCKTEQDLALGTDAEGQK VKDSMRVLLPVLLNKNHDNC DKIRAILLYIFSINGTTEEN LDRLIQNVKIENESDMIRNW SYLGVPIVPQSQQGKPLRKD RSAEETFQLSRWTPFIKDIM EDAIDNRLDSKEWPYCSQCP AVWNGSGAVSARQKPRANYL EDRKNGSKLIVFVIGGITYS EVRCAYEVSQAHKSCEVIIG STHVLTPKKLLDDIKMLNK |
| Tissue Specificity | Megakaryocytes and platelets. |
| Post Translational Modifications | Phosphorylated by PKC in platelets in response to thrombin stimulation.phosphorylation inhibits binding to STX4. |
| Function | Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes. |
| Protein Name | Syntaxin-Binding Protein 3Platelet Sec1 ProteinPspProtein Unc-18 Homolog 3Unc18-3Protein Unc-18 Homolog CUnc-18c |
| Database Links | Reactome: R-HSA-114516Reactome: R-HSA-1445148 |
| Cellular Localisation | CytoplasmCytosolCell MembraneIn PlateletsPredominantly CytosolicLow Amounts Membrane-Associated |
| Alternative Antibody Names | Anti-Syntaxin-Binding Protein 3 antibodyAnti-Platelet Sec1 Protein antibodyAnti-Psp antibodyAnti-Protein Unc-18 Homolog 3 antibodyAnti-Unc18-3 antibodyAnti-Protein Unc-18 Homolog C antibodyAnti-Unc-18c antibodyAnti-STXBP3 antibody |
Information sourced from Uniprot.org