| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
STXBP2 |
| Gene ID: |
6813 |
| Uniprot ID: |
STXB2_HUMAN |
| Immunogen Region: |
1-280 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human STXBP2 (NP_001120868.1). |
| Immunogen Sequence: |
MAPSGLKAVVGEKILSGVIR SVKKDGEWKVLIMDHPSMRI LSSCCKMSDILAEGITIVED INKRREPIPSLEAIYLLSPT EKALIKDFQGTPTFTYKAAH IFFTDTCPEPLFSELGRSRL AKVVKTLKEIHLAFLPYEAQ VFSLDAPHSTYNLYCPFRAE ERTRQLEVLAQQIATLCATL QEYPAIRYRKGPEDTAQLAH AVLAKLNAFKADTPSLGEGP EKTRSQLLIMDRAADPVSP |
| Tissue Specificity | Placenta, lung, liver, kidney and pancreas, as well as in peripheral blood lymphocytes. |
| Function | Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells. |
| Protein Name | Syntaxin-Binding Protein 2Protein Unc-18 Homolog 2Unc18-2Protein Unc-18 Homolog BUnc-18b |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-449836 |
| Alternative Antibody Names | Anti-Syntaxin-Binding Protein 2 antibodyAnti-Protein Unc-18 Homolog 2 antibodyAnti-Unc18-2 antibodyAnti-Protein Unc-18 Homolog B antibodyAnti-Unc-18b antibodyAnti-STXBP2 antibodyAnti-UNC18B antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
