| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | STXBP2 |
| Gene ID: | 6813 |
| Uniprot ID: | STXB2_HUMAN |
| Immunogen Region: | 1-280 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human STXBP2 (NP_001120868.1). |
| Immunogen Sequence: | MAPSGLKAVVGEKILSGVIR SVKKDGEWKVLIMDHPSMRI LSSCCKMSDILAEGITIVED INKRREPIPSLEAIYLLSPT EKALIKDFQGTPTFTYKAAH IFFTDTCPEPLFSELGRSRL AKVVKTLKEIHLAFLPYEAQ VFSLDAPHSTYNLYCPFRAE ERTRQLEVLAQQIATLCATL QEYPAIRYRKGPEDTAQLAH AVLAKLNAFKADTPSLGEGP EKTRSQLLIMDRAADPVSP |
| Tissue Specificity | Placenta, lung, liver, kidney and pancreas, as well as in peripheral blood lymphocytes. |
| Function | Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells. |
| Protein Name | Syntaxin-Binding Protein 2Protein Unc-18 Homolog 2Unc18-2Protein Unc-18 Homolog BUnc-18b |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-449836 |
| Alternative Antibody Names | Anti-Syntaxin-Binding Protein 2 antibodyAnti-Protein Unc-18 Homolog 2 antibodyAnti-Unc18-2 antibodyAnti-Protein Unc-18 Homolog B antibodyAnti-Unc-18b antibodyAnti-STXBP2 antibodyAnti-UNC18B antibody |
Information sourced from Uniprot.org