• Western blot analysis of extracts of various cell lines, using STXBP2 antibody (STJ110046) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-STXBP2 antibody (1-280) (STJ110046)

SKU:
STJ110046

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-STXBP2 (1-280) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: STXBP2
Gene ID: 6813
Uniprot ID: STXB2_HUMAN
Immunogen Region: 1-280
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human STXBP2 (NP_001120868.1).
Immunogen Sequence: MAPSGLKAVVGEKILSGVIR SVKKDGEWKVLIMDHPSMRI LSSCCKMSDILAEGITIVED INKRREPIPSLEAIYLLSPT EKALIKDFQGTPTFTYKAAH IFFTDTCPEPLFSELGRSRL AKVVKTLKEIHLAFLPYEAQ VFSLDAPHSTYNLYCPFRAE ERTRQLEVLAQQIATLCATL QEYPAIRYRKGPEDTAQLAH AVLAKLNAFKADTPSLGEGP EKTRSQLLIMDRAADPVSP
Tissue Specificity Placenta, lung, liver, kidney and pancreas, as well as in peripheral blood lymphocytes.
Function Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells.
Protein Name Syntaxin-Binding Protein 2
Protein Unc-18 Homolog 2
Unc18-2
Protein Unc-18 Homolog B
Unc-18b
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-449836
Alternative Antibody Names Anti-Syntaxin-Binding Protein 2 antibody
Anti-Protein Unc-18 Homolog 2 antibody
Anti-Unc18-2 antibody
Anti-Protein Unc-18 Homolog B antibody
Anti-Unc-18b antibody
Anti-STXBP2 antibody
Anti-UNC18B antibody

Information sourced from Uniprot.org

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