| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | STX8 |
| Gene ID: | 9482 |
| Uniprot ID: | STX8_HUMAN |
| Immunogen Region: | 1-215 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of human STX8 (NP_004844.1). |
| Immunogen Sequence: | MAPDPWFSTYDSTCQIAQEI AEKIQQRNQYERKGEKAPKL TVTIRALLQNLKEKIALLKD LLLRAVSTHQITQLEGDRRQ NLLDDLVTRERLLLASFKNE GAEPDLIRSSLMSEEAKRGA PNPWLFEEPEETRGLGFDEI RQQQQKIIQEQDAGLDALSS IISRQKQMGQEIGNELDEQN EIIDDLANLVENTDEKLRNE TRRVNMVDRKSASCG |
| Tissue Specificity | Highly expressed in heart. Also found in brain, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas. |
| Post Translational Modifications | Ubiquitinated by HECTD3. |
| Function | Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER. |
| Protein Name | Syntaxin-8 |
| Cellular Localisation | MembraneSingle-Pass Type Iv Membrane ProteinPreferentially Associated With The Early EndosomeTo A Lesser ExtentAlso Present In Late EndosomeThe Plasma Membrane And Coated Pits |
| Alternative Antibody Names | Anti-Syntaxin-8 antibodyAnti-STX8 antibody |
Information sourced from Uniprot.org