| Short Description : | Rabbit polyclonal anti-STE20-related kinase adapter protein beta (313-363 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | STRADB |
| Gene ID: | 55437 |
| Uniprot ID: | STRAB_HUMAN |
| Immunogen: | Synthesized peptide derived from the human STRAB at the amino acid range 313-363 |
| Immunogen Region: | 313-363 aa |
| Specificity: | This antibody detects endogenous levels of STRAB at Human/Mouse |
| Function | Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. |
| Protein Name | Ste20-Related Kinase Adapter Protein BetaStrad BetaAmyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 2 ProteinCals-21Ilp-Interacting ProteinPseudokinase Als2cr2 |
| Database Links | Reactome: R-HSA-380972 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Ste20-Related Kinase Adapter Protein Beta antibodyAnti-Strad Beta antibodyAnti-Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 2 Protein antibodyAnti-Cals-21 antibodyAnti-Ilp-Interacting Protein antibodyAnti-Pseudokinase Als2cr2 antibodyAnti-STRADB antibodyAnti-ALS2CR2 antibodyAnti-ILPIP antibodyAnti-PRO1038 antibody |
Information sourced from Uniprot.org
