Anti-STRA8 antibody (151-200 aa) (STJ97252)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human STRA8 at the amino acid range 151-200
General Information
| Short Description | Rabbit polyclonal anti-Stimulated by retinoic acid gene 8 protein homolog (151-200 aa) for use in WB and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | STRA8 |
| Gene ID | 346673 |
| Uniprot ID | STRA8_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human STRA8 at the amino acid range 151-200 |
| Immunogen Region | 151-200 aa |
| Specificity | Stra8 Polyclonal Antibody detects endogenous levels of Stra8 protein. |
Additional Info
| Post Translational Modifications | Phosphorylated. |
| Function | Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, acts downstream of ZGLP1 as a key effector of the meiotic program: required for premeiotic DNA replication and subsequent events in meiotic prophase. During spermatogenesis, next to its role in meiotic initiation, promotes (but is not required for) spermatogonial differentiation. In complex with MEIOSIN, directly activates the transcription of a subset of critical meiotic genes playing a central role in cell-cycle switching from mitosis to meiosis. |
| Protein Name | Stimulated By Retinoic Acid Gene 8 Protein Homolog |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusShuttles Between Nucleus And CytoplasmNuclear Export Is Xpo1-Dependent |
| Alternative Antibody Names | Anti-Stimulated By Retinoic Acid Gene 8 Protein Homolog antibodyAnti-STRA8 antibody |
Information sourced from Uniprot.org