| Short Description : | Rabbit polyclonal STAR (64-285) antibody for use in WB, IP and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IP/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | STAR |
| Gene ID: | 6770 |
| Uniprot ID: | STAR_HUMAN |
| Immunogen Region: | 64-285 |
| Immunogen Sequence: | EETLYSDQELAYLQQGEEAM QKALGILSNQEGWKKESQQD NGDKVMSKVVPDVGKVFRLE VVVDQPMERLYEELVERMEA MGEWNPNVKEIKVLQKIGKD TFITHELAAEAAGNLVGPRD FVSVRCAKRRGSTCVLAGMA TDFGNMPEQKGVIRAEHGPT CMVLHPLAGSPSKTKLTWLL SIDLKGWLPKSIINQVLSQT QVDFANHLRKRLESHPASEA RC |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 64-285 of human StAR (NP_000340.2). |
| Tissue Specificity | Expressed in gonads, adrenal cortex and kidney. |
| Function | Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. |
| Protein Name | Steroidogenic Acute Regulatory Protein - MitochondrialStarStart Domain-Containing Protein 1Stard1 |
| Database Links | Reactome: R-HSA-196108Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Steroidogenic Acute Regulatory Protein - Mitochondrial antibodyAnti-Star antibodyAnti-Start Domain-Containing Protein 1 antibodyAnti-Stard1 antibodyAnti-STAR antibodyAnti-STARD1 antibody |
Information sourced from Uniprot.org
