| Short Description : | Rabbit polyclonal SSPN (1-60) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SSPN |
| Gene ID: | 8082 |
| Uniprot ID: | SSPN_HUMAN |
| Immunogen Region: | 1-60 |
| Immunogen Sequence: | MGKNKQPRGQQRQGGPPAAD AAGPDDMEPKKGTGAPKECG EEEPRTCCGCRFPLLLALLQ |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-60 of human SSPN (NP_005077.2). |
| Tissue Specificity | Isoform 1 is expressed exclusively in heart and skeletal muscle. Isoform 2 is expressed in heart, skeletal muscle, thymus, prostate, testis, ovary, small intestine, colon and spleen. |
| Function | Component of the dystrophin-glycoprotein complex (DGC), a complex that spans the muscle plasma membrane and forms a link between the F-actin cytoskeleton and the extracellular matrix. Preferentially associates with the sarcoglycan subcomplex of the DGC. |
| Protein Name | SarcospanK-Ras Oncogene-Associated ProteinKirsten-Ras-Associated Protein |
| Database Links | Reactome: R-HSA-9913351 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinSarcolemmaPostsynaptic Cell MembraneAlso Found In Myotendinous Junctions And In The Postsynaptic Membrane Of Neuromuscular Junctions |
| Alternative Antibody Names | Anti-Sarcospan antibodyAnti-K-Ras Oncogene-Associated Protein antibodyAnti-Kirsten-Ras-Associated Protein antibodyAnti-SSPN antibodyAnti-KRAG antibody |
Information sourced from Uniprot.org
