| Host: |
Mouse |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-SSB (2-408 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
4B10-E11-H11 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1 |
| Formulation: |
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Purification: |
Affinity Purified |
| Concentration: |
2.65 mg/ml |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: |
SSB |
| Gene ID: |
6741 |
| Uniprot ID: |
LA_HUMAN |
| Immunogen Region: |
2-408 aa |
| Immunogen: |
Purified recombinant human La Antigen protein fragments expressed in E.coli. |
| Post Translational Modifications | Phosphorylated. The phosphorylation sites are at the C-terminal part of the protein. The N-terminus is blocked. |
| Function | Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation. In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation. |
| Protein Name | Lupus La ProteinLa AutoantigenLa RibonucleoproteinSjoegren Syndrome Type B AntigenSs-B |
| Database Links | Reactome: R-HSA-73980Reactome: R-HSA-749476 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Lupus La Protein antibodyAnti-La Autoantigen antibodyAnti-La Ribonucleoprotein antibodyAnti-Sjoegren Syndrome Type B Antigen antibodyAnti-Ss-B antibodyAnti-SSB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
