Anti-SRSF6 antibody (30-110 aa) (STJ95785)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from SRp55 at the amino acid range 30-110
STJ95785
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General Information

Short DescriptionRabbit polyclonal anti-Serine/arginine-rich splicing factor 6 (30-110 aa) for use in IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsIHC/IF/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeIHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolSRSF6
Gene ID6431
Uniprot IDSRSF6_HUMAN
ImmunogenSynthesized peptide derived from SRp55 at the amino acid range 30-110
Immunogen Region30-110 aa
SpecificitySRp55 Polyclonal Antibody detects endogenous levels of SRp55 protein.

Additional Info

Function Plays a role in constitutive splicing and modulates the selection of alternative splice sites. Plays a role in the alternative splicing of MAPT/Tau exon 10. Binds to alternative exons of TNC pre-mRNA and promotes the expression of alternatively spliced TNC. Plays a role in wound healing and in the regulation of keratinocyte differentiation and proliferation via its role in alternative splicing.
Protein Name Serine/Arginine-Rich Splicing Factor 6
Pre-Mrna-Splicing Factor Srp55
Splicing Factor - Arginine/Serine-Rich 6
Database Links Reactome: R-HSA-159236
Reactome: R-HSA-72163
Reactome: R-HSA-72165
Reactome: R-HSA-72187
Reactome: R-HSA-72203
Reactome: R-HSA-73856
Cellular Localisation Nucleus
Nucleus Speckle
Alternative Antibody Names Anti-Serine/Arginine-Rich Splicing Factor 6 antibody
Anti-Pre-Mrna-Splicing Factor Srp55 antibody
Anti-Splicing Factor - Arginine/Serine-Rich 6 antibody
Anti-SRSF6 antibody
Anti-SFRS6 antibody
Anti-SRP55 antibody

Information sourced from Uniprot.org

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