| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SRP14 |
| Gene ID: | 6727 |
| Uniprot ID: | SRP14_HUMAN |
| Immunogen Region: | 1-136 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-136 of human SRP14 (NP_003125.3). |
| Immunogen Sequence: | MVLLESEQFLTELTRLFQKC RTSGSVYITLKKYDGRTKPI PKKGTVEGFEPADNKCLLRA TDGKKKISTVVSSKEVNKFQ MAYSNLLRANMDGLKKRDKK NKTKKTKAAAAAAAAAPAAA ATAPTTAATTAATAAQ |
| Function | Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. |
| Protein Name | Signal Recognition Particle 14 Kda ProteinSrp1418 Kda Alu Rna-Binding Protein |
| Database Links | Reactome: R-HSA-1799339Reactome: R-HSA-6798695 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Signal Recognition Particle 14 Kda Protein antibodyAnti-Srp14 antibodyAnti-18 Kda Alu Rna-Binding Protein antibodyAnti-SRP14 antibody |
Information sourced from Uniprot.org