| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SRA1 (1-100) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:100-1:500 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SRA1 |
| Gene ID: |
10011 |
| Uniprot ID: |
SRA1_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SRA1 (NP_001030312.2). |
| Immunogen Sequence: |
MTRCPAGQAEVEMAELYVKP GNKERGWNDPPQFSYGLQTQ AGGPRRSLLTKRVAAPQDGS PRVPASETSPGPPPMGPPPP SSKAPRSPPVGSGPASGVEP |
| Tissue Specificity | Highly expressed in liver and skeletal muscle and to a lesser extent in brain. Also expressed in both normal and tumorigenic breast epithelial cell lines. Significantly up-regulated in human tumors of the breast, ovary, and uterus. |
| Function | Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis. |
| Protein Name | Steroid Receptor Rna Activator 1Steroid Receptor Rna Activator ProteinSrap |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Steroid Receptor Rna Activator 1 antibodyAnti-Steroid Receptor Rna Activator Protein antibodyAnti-Srap antibodyAnti-SRA1 antibodyAnti-PP7684 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
