| Short Description : | Rabbit polyclonal SPZ1 (1-430) antibody for use in WB and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SPZ1 |
| Gene ID: | 84654 |
| Uniprot ID: | SPZ1_HUMAN |
| Immunogen Region: | 1-430 |
| Immunogen Sequence: | MASSAKSAEMPTISKTVNPT PDPHQEYLDPRITIALFEIG SHSPSSWGSLPFLKNSSHQV TEQQTAQKFNNLLKEIKDIL KNMAGFEEKITEAKELFEET NITEDVSAHKENIRGLDKIN EMLSTNLPVSLAPEKEDNEK KQEMILETNITEDVSAHKEN IRGLDKINEMLSTNLPVSLA PEKEDNEKKQQMIMENQNSE NTAQVFARDLVNRLEEKKVL NETQQSQEKAKNRLNVQEE |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-430 of human SPZ1 (NP_115956.3). |
| Tissue Specificity | Specifically and strongly expressed in the testis. Expressed in several tumor cell lines. |
| Post Translational Modifications | Phosphorylated by MAPK1/ERK2 and MAPK3/ERK1. |
| Function | Transcription factor that binds to the DNA sequence 5'-CANNTG-3'(E box) and the G-box motif. May play an important role in the regulation of cell proliferation and differentiation during spermatogenesis. |
| Protein Name | Spermatogenic Leucine Zipper Protein 1Testis-Specific Protein 1Testis-Specific Protein Nyd-Tsp1 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Spermatogenic Leucine Zipper Protein 1 antibodyAnti-Testis-Specific Protein 1 antibodyAnti-Testis-Specific Protein Nyd-Tsp1 antibodyAnti-SPZ1 antibodyAnti-TSP1 antibody |
Information sourced from Uniprot.org
