• Western blot analysis of the lysates from Jurkat cells using SPTBN1 antibody.
  • Western blot analysis of lysates from COLO cells, using SPTBN1 Antibody. The lane on the right is blocked with the synthesized peptide.

Anti-SPTBN1 antibody (651-700 aa) (STJ95746)

SKU:
STJ95746

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Spectrin beta chain, non-erythrocytic 1 (651-700 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SPTBN1
Gene ID: 6711
Uniprot ID: SPTB2_HUMAN
Immunogen Region: 651-700 aa
Specificity: Spectrin Beta II Polyclonal Antibody detects endogenous levels of Spectrin Beta II protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human SPTBN1 at the amino acid range 651-700
Function Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. Plays a critical role in central nervous system development and function.
Protein Name Spectrin Beta Chain - Non-Erythrocytic 1
Beta-Ii Spectrin
Fodrin Beta Chain
Spectrin - Non-Erythroid Beta Chain 1
Database Links Reactome: R-HSA-373753
Reactome: R-HSA-375165
Reactome: R-HSA-445095
Reactome: R-HSA-5673001
Reactome: R-HSA-6807878
Reactome: R-HSA-9013420
Reactome: R-HSA-9013424
Reactome: R-HSA-9662360
Reactome: R-HSA-9662361
Reactome: R-HSA-9703465
Cellular Localisation Cytoplasm
Cytoskeleton
Myofibril
Sarcomere
M Line
Cytosol
Cell Membrane
Colocalizes With Ank2 In A Distinct Intracellular Compartment Of Neonatal Cardiomyocytes
Isoform 2: Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Alternative Antibody Names Anti-Spectrin Beta Chain - Non-Erythrocytic 1 antibody
Anti-Beta-Ii Spectrin antibody
Anti-Fodrin Beta Chain antibody
Anti-Spectrin - Non-Erythroid Beta Chain 1 antibody
Anti-SPTBN1 antibody
Anti-SPTB2 antibody

Information sourced from Uniprot.org

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