Anti-splicing factor 1 antibody [2F5D10] (STJ16103542)

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STJ16103542-100
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Host: Mouse
Applications: WB/IHC/ICC/IF/FC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal anti-splicing factor 1 for use in WB, IHC, ICC, IF and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : 2F5D10
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. NA
Purification: Lyophilized
Concentration: Adding 0.2 mL of distilled water =f 500 Mu g/mL.
Storage Instruction: Store at-20°C for up to 1 year. Minimise freeze-thaw cycles.
Gene Symbol: SF1
Gene ID: 7536
Uniprot ID: SF01_HUMAN
Immunogen: E. coli-derived human splicing factor 1 recombinant protein (Position: R160-Q266).
Post Translational Modifications Phosphorylation on Ser-20 interferes with U2AF2 binding and spliceosome assembly. Isoform 6 is phosphorylated on Ser-463.
Function Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor.
Protein Name Splicing Factor 1
Mammalian Branch Point-Binding Protein
Bbp
Mbbp
Transcription Factor Zfm1
Zinc Finger Gene In Men1 Locus
Zinc Finger Protein 162
Database Links Reactome: R-HSA-72163
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Splicing Factor 1 antibody
Anti-Mammalian Branch Point-Binding Protein antibody
Anti-Bbp antibody
Anti-Mbbp antibody
Anti-Transcription Factor Zfm1 antibody
Anti-Zinc Finger Gene In Men1 Locus antibody
Anti-Zinc Finger Protein 162 antibody
Anti-SF1 antibody
Anti-ZFM1 antibody
Anti-ZNF162 antibody

Information sourced from Uniprot.org

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