Anti-SPAM1 antibody [SRM14501] (STJ11109231)

SKU:
STJ11109231
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Host: Rabbit
Applications: WB/IHC-P/ELISA
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : SRM14501
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity purification
Dilution Range: WB, 1:1000-1:4000
IHC-P, 1:500-1:1000
ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SPAM1
Gene ID: 6677
Uniprot ID: HYALP_HUMAN
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tissue Specificity Testis.
Post Translational Modifications N-glycosylated.
Function Involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. This protein aids in penetrating the layer of cumulus cells by digesting hyaluronic acid.
Protein Name Hyaluronidase Ph-20
Hyal-Ph20
Hyaluronoglucosaminidase Ph-20
Sperm Adhesion Molecule 1
Sperm Surface Protein Ph-20
Database Links Reactome: R-HSA-2534343
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Alternative Antibody Names Anti-Hyaluronidase Ph-20 antibody
Anti-Hyal-Ph20 antibody
Anti-Hyaluronoglucosaminidase Ph-20 antibody
Anti-Sperm Adhesion Molecule 1 antibody
Anti-Sperm Surface Protein Ph-20 antibody
Anti-SPAM1 antibody
Anti-HYAL3 antibody
Anti-PH20 antibody

Information sourced from Uniprot.org