Anti-SPAM1 antibody [PT0768R] (STJA0039329)

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STJA0039329
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Hyaluronidase Ph-20 is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality : Monoclonal
Clone ID : PT0768R
Conjugation: Unconjugated
Isotype: IgGk
Formulation: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Purification: Protein A
Dilution Range: WB 1:1000-5000
IHC 1:100-300
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SPAM1
Gene ID: 6677
Uniprot ID: HYALP_HUMAN
Specificity: Endogenous
Post Translational Modifications N-glycosylated.
Function Involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. This protein aids in penetrating the layer of cumulus cells by digesting hyaluronic acid.
Protein Name Hyaluronidase Ph-20
Hyal-Ph20
Hyaluronoglucosaminidase Ph-20
Sperm Adhesion Molecule 1
Sperm Surface Protein Ph-20
Database Links Reactome: R-HSA-2534343
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Alternative Antibody Names Anti-Hyaluronidase Ph-20 antibody
Anti-Hyal-Ph20 antibody
Anti-Hyaluronoglucosaminidase Ph-20 antibody
Anti-Sperm Adhesion Molecule 1 antibody
Anti-Sperm Surface Protein Ph-20 antibody
Anti-SPAM1 antibody
Anti-HYAL3 antibody
Anti-PH20 antibody

Information sourced from Uniprot.org