Anti-SNU13 antibody (33-83 aa) (STJ195482)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human NH2L1 at the amino acid range 33-83
General Information
| Short Description | Rabbit polyclonal anti-NHP2-like protein 1 (33-83 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SNU13 |
| Gene ID | 4809 |
| Uniprot ID | NH2L1_HUMAN |
| Immunogen | Synthesized peptide derived from the human NH2L1 at the amino acid range 33-83 |
| Immunogen Region | 33-83 aa |
| Specificity | This antibody detects endogenous levels of NH2L1 at Human/Mouse/Rat |
Additional Info
| Function | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in pre-mRNA splicing as component of the spliceosome. Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly. The protein undergoes a conformational change upon RNA-binding. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) complexes that function in methylation of multiple sites on ribosomal RNAs (rRNAs) and messenger RNAs (mRNAs). |
| Protein Name | Nhp2-Like Protein 1High Mobility Group-Like Nuclear Protein 2 Homolog 1Otk27Snu13 HomologHsnu13U4/U6.U5 Small Nuclear Ribonucleoprotein Snu13U4/U6.U5 Tri-Snrnp 15.5 Kda Protein Cleaved Into - Nhp2-Like Protein 1 - N-Terminally Processed |
| Database Links | Reactome: R-HSA-6790901Reactome: R-HSA-6791226Reactome: R-HSA-72163 |
| Cellular Localisation | NucleusNucleolusConcentrated In The Dense Fibrillar Component Of The Nucleolus |
| Alternative Antibody Names | Anti-Nhp2-Like Protein 1 antibodyAnti-High Mobility Group-Like Nuclear Protein 2 Homolog 1 antibodyAnti-Otk27 antibodyAnti-Snu13 Homolog antibodyAnti-Hsnu13 antibodyAnti-U4/U6.U5 Small Nuclear Ribonucleoprotein Snu13 antibodyAnti-U4/U6.U5 Tri-Snrnp 15.5 Kda Protein Cleaved Into - Nhp2-Like Protein 1 - N-Terminally Processed antibodyAnti-SNU13 antibodyAnti-NHP2L1 antibody |
Information sourced from Uniprot.org